A11T (p.Ala11Thr) variant of CD8B (P10966)
A11T (p.Ala11Thr) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A11T (p.Ala11Thr) variant details
- p.Ala11Thr
- gnomAD rs1273262945
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.06
- MetaLR 0.15
- MetaSVM -0.99
- CADD 16.70
- PolyPhen-2 0.68
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available