A10D (p.Ala10Asp) variant of CD8B (P10966)
A10D (p.Ala10Asp) in CD8B (P10966) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A10D (p.Ala10Asp) variant details
- p.Ala10Asp
- TOPMed rs1483060992
- gnomAD rs1483060992
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.30
- MetaLR 0.22
- MetaSVM -0.99
- CADD 22.60
- PolyPhen-2 0.29
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 0.0001)
- Structural context available