Y112H (p.Tyr112His) variant of CD8A (P01732)
Y112H (p.Tyr112His) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data.
Y112H (p.Tyr112His) variant details
- p.Tyr112His
- TOPMed rs1377480811
- gnomAD rs1377480811
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.40
- MetaLR 0.32
- MetaSVM -0.43
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 0.00048)