Y112C (p.Tyr112Cys) variant of CD8A (P01732)
Y112C (p.Tyr112Cys) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data.
Y112C (p.Tyr112Cys) variant details
- p.Tyr112Cys
- TOPMed rs17852285
- gnomAD rs17852285
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.45
- MetaLR 0.42
- MetaSVM -0.16
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)