V45A (p.Val45Ala) variant of CD8A (P01732)
V45A (p.Val45Ala) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
V45A (p.Val45Ala) variant details
- p.Val45Ala
- ExAC rs745865801
- TOPMed rs745865801
- gnomAD rs745865801
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.19
- MetaLR 0.15
- MetaSVM -0.90
- CADD 18.70
- PolyPhen-2 0.37
- SIFT 0.06
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available