S90L (p.Ser90Leu) variant of CD8A (P01732)
S90L (p.Ser90Leu) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S90L (p.Ser90Leu) variant details
- p.Ser90Leu
- cosmic curated COSV52158
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.16
- MetaLR 0.50
- MetaSVM -0.78
- CADD 18.90
- PolyPhen-2 0.97
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available