S66C (p.Ser66Cys) variant of CD8A (P01732)
S66C (p.Ser66Cys) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data.
S66C (p.Ser66Cys) variant details
- p.Ser66Cys
- TOPMed rs1673239203
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.20
- MetaLR 0.32
- MetaSVM -0.58
- CADD 13.70
- PolyPhen-2 0.51
- SIFT 0.02
- Most common in the East Asian population (allele frequency 0.00015)