S55W (p.Ser55Trp) variant of CD8A (P01732)
S55W (p.Ser55Trp) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
S55W (p.Ser55Trp) variant details
- p.Ser55Trp
- ExAC rs750103978
- TOPMed rs750103978
- gnomAD rs750103978
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.40
- MetaLR 0.52
- MetaSVM 0.17
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available