S52L (p.Ser52Leu) variant of CD8A (P01732)
S52L (p.Ser52Leu) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
S52L (p.Ser52Leu) variant details
- p.Ser52Leu
- ExAC rs200195023
- gnomAD rs200195023
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.09
- MetaLR 0.16
- MetaSVM -0.85
- CADD 18.30
- PolyPhen-2 0.56
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available