S48F (p.Ser48Phe) variant of CD8A (P01732)
S48F (p.Ser48Phe) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S48F (p.Ser48Phe) variant details
- p.Ser48Phe
- ExAC rs757331415
- gnomAD rs757331415
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.17
- MetaLR 0.54
- MetaSVM -0.63
- CADD 22.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available