S48A (p.Ser48Ala) variant of CD8A (P01732)
S48A (p.Ser48Ala) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S48A (p.Ser48Ala) variant details
- p.Ser48Ala
- gnomAD rs1174295473
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.19
- MetaLR 0.46
- MetaSVM -0.23
- CADD 0.81
- PolyPhen-2 0.54
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available