R25W (p.Arg25Trp) variant of CD8A (P01732)
R25W (p.Arg25Trp) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R25W (p.Arg25Trp) variant details
- p.Arg25Trp
- gnomAD rs1428537849
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.24
- MetaLR 0.28
- MetaSVM -0.43
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available