R106H (p.Arg106His) variant of CD8A (P01732)
R106H (p.Arg106His) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data.
R106H (p.Arg106His) variant details
- p.Arg106His
- cosmic curated COSV52156
- TOPMed rs1227939880
- gnomAD rs1227939880
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.08
- MetaLR 0.14
- MetaSVM -0.98
- CADD 12.50
- PolyPhen-2 0.02
- SIFT 0.04
- Most common in the 1KG:CLM population (allele frequency 0.0053)