P50L (p.Pro50Leu) variant of CD8A (P01732)
P50L (p.Pro50Leu) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
P50L (p.Pro50Leu) variant details
- p.Pro50Leu
- gnomAD rs1043882597
- Missense
- Variant Prioritization Score for Impact Estimate 0.0796
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.08
- CADD 0.45
- PolyPhen-2 0.00
- SIFT 0.74
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available