P21R (p.Pro21Arg) variant of CD8A (P01732)
P21R (p.Pro21Arg) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data.
P21R (p.Pro21Arg) variant details
- p.Pro21Arg
- ExAC rs764996911
- TOPMed rs764996911
- gnomAD rs764996911
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.13
- MetaLR 0.36
- MetaSVM -0.80
- CADD 9.39
- PolyPhen-2 0.05
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)