L9P (p.Leu9Pro) variant of CD8A (P01732)
L9P (p.Leu9Pro) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- TOPMed rs1339275163
- gnomAD rs1339275163
- Missense
- Variant Prioritization Score for Impact Estimate 0.725
- REVEL 0.83
- MetaLR 0.71
- MetaSVM 0.51
- CADD 31.00
- PolyPhen-2 0.97
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00031)