L70F (p.Leu70Phe) variant of CD8A (P01732)
L70F (p.Leu70Phe) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L70F (p.Leu70Phe) variant details
- p.Leu70Phe
- cosmic curated COSV10462
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.24
- MetaLR 0.46
- MetaSVM -0.55
- CADD 23.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available