L57F (p.Leu57Phe) variant of CD8A (P01732)
L57F (p.Leu57Phe) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L57F (p.Leu57Phe) variant details
- p.Leu57Phe
- TOPMed rs986711829
- gnomAD rs986711829
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.26
- MetaLR 0.26
- MetaSVM -0.58
- CADD 23.60
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available