L41V (p.Leu41Val) variant of CD8A (P01732)
L41V (p.Leu41Val) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data.
L41V (p.Leu41Val) variant details
- p.Leu41Val
- Ensembl rs1052718780
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.51
- MetaLR 0.54
- MetaSVM -0.37
- CADD 21.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00012)