L15R (p.Leu15Arg) variant of CD8A (P01732)
L15R (p.Leu15Arg) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data.
L15R (p.Leu15Arg) variant details
- p.Leu15Arg
- TOPMed rs1673265301
- gnomAD rs1673265301
- Missense
- Variant Prioritization Score for Impact Estimate 0.555
- REVEL 0.69
- MetaLR 0.61
- MetaSVM -0.24
- CADD 25.60
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00015)