I122V (p.Ile122Val) variant of CD8A (P01732)
I122V (p.Ile122Val) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
I122V (p.Ile122Val) variant details
- p.Ile122Val
- ESP rs199855213
- ExAC rs199855213
- TOPMed rs199855213
- gnomAD rs199855213
- Missense
- Variant Prioritization Score for Impact Estimate 0.086
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -0.92
- CADD 0.02
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available