I122L (p.Ile122Leu) variant of CD8A (P01732)
I122L (p.Ile122Leu) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I122L (p.Ile122Leu) variant details
- p.Ile122Leu
- ESP rs199855213
- ExAC rs199855213
- TOPMed rs199855213
- gnomAD rs199855213
- Missense
- Variant Prioritization Score for Impact Estimate 0.0972
- REVEL 0.04
- MetaLR 0.09
- MetaSVM -1.00
- CADD 7.21
- PolyPhen-2 0.13
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available