G83R (p.Gly83Arg) variant of CD8A (P01732)
G83R (p.Gly83Arg) in CD8A (P01732) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G83R (p.Gly83Arg) variant details
- p.Gly83Arg
- rs750058603
- ExAC rs750058603
- TOPMed rs750058603
- gnomAD rs750058603
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.14
- MetaLR 0.32
- MetaSVM -0.91
- CADD 15.80
- PolyPhen-2 0.76
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available