G53S (p.Gly53Ser) variant of CD8A (P01732)
G53S (p.Gly53Ser) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G53S (p.Gly53Ser) variant details
- p.Gly53Ser
- ExAC rs765952408
- gnomAD rs765952408
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.07
- MetaLR 0.20
- MetaSVM -0.92
- CADD 14.90
- PolyPhen-2 0.88
- SIFT 0.13
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available