F89L (p.Phe89Leu) variant of CD8A (P01732)
F89L (p.Phe89Leu) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
F89L (p.Phe89Leu) variant details
- p.Phe89Leu
- ExAC rs764628330
- TOPMed rs764628330
- gnomAD rs764628330
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.23
- MetaLR 0.22
- MetaSVM -0.85
- CADD 9.30
- PolyPhen-2 0.04
- SIFT 0.19
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available