F69V (p.Phe69Val) variant of CD8A (P01732)
F69V (p.Phe69Val) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
F69V (p.Phe69Val) variant details
- p.Phe69Val
- TOPMed rs1673238545
- gnomAD rs1673238545
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.16
- MetaLR 0.19
- MetaSVM -0.96
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available