F105L (p.Phe105Leu) variant of CD8A (P01732)
F105L (p.Phe105Leu) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data.
F105L (p.Phe105Leu) variant details
- p.Phe105Leu
- gnomAD rs1233238261
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.28
- MetaLR 0.15
- MetaSVM -1.00
- CADD 22.50
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)