D85Y (p.Asp85Tyr) variant of CD8A (P01732)
D85Y (p.Asp85Tyr) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
D85Y (p.Asp85Tyr) variant details
- p.Asp85Tyr
- gnomAD rs1318750582
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.13
- MetaLR 0.23
- MetaSVM -0.91
- CADD 18.00
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available