C54S (p.Cys54Ser) variant of CD8A (P01732)
C54S (p.Cys54Ser) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
C54S (p.Cys54Ser) variant details
- p.Cys54Ser
- gnomAD rs1201564636
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.33
- MetaLR 0.35
- MetaSVM -0.31
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available