A19T (p.Ala19Thr) variant of CD8A (P01732)
A19T (p.Ala19Thr) in CD8A (P01732) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data.
A19T (p.Ala19Thr) variant details
- p.Ala19Thr
- TOPMed rs1161733294
- gnomAD rs1161733294
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.25
- MetaLR 0.30
- MetaSVM -0.82
- CADD 8.93
- PolyPhen-2 0.02
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 0.00041)