V74A (p.Val74Ala) variant of CD79B (P40259)
V74A (p.Val74Ala) in CD79B (P40259) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
V74A (p.Val74Ala) variant details
- p.Val74Ala
- TOPMed rs1374827449
- gnomAD rs1374827449
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.44
- CADD 23.60
- PolyPhen-2 0.83
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available