R57Q (p.Arg57Gln) variant of CD79B (P40259)
R57Q (p.Arg57Gln) in CD79B (P40259) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R57Q (p.Arg57Gln) variant details
- p.Arg57Gln
- ExAC rs746592632
- TOPMed rs746592632
- gnomAD rs746592632
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.22
- AlphaMissense 0.55
- MetaLR 0.33
- MetaSVM -0.54
- CADD 26.00
- PolyPhen-2 1.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available