R57L (p.Arg57Leu) variant of CD79B (P40259)
R57L (p.Arg57Leu) in CD79B (P40259) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R57L (p.Arg57Leu) variant details
- p.Arg57Leu
- ExAC rs746592632
- TOPMed rs746592632
- gnomAD rs746592632
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.23
- AlphaMissense 0.55
- MetaLR 0.33
- MetaSVM -0.54
- CADD 25.80
- PolyPhen-2 1.00
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available