R55S (p.Arg55Ser) variant of CD79B (P40259)
R55S (p.Arg55Ser) in CD79B (P40259) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R55S (p.Arg55Ser) variant details
- p.Arg55Ser
- ExAC rs747800058
- gnomAD rs747800058
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.12
- CADD 21.20
- PolyPhen-2 0.25
- SIFT 0.11
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available