R45W (p.Arg45Trp) variant of CD79B (P40259)
R45W (p.Arg45Trp) in CD79B (P40259) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R45W (p.Arg45Trp) variant details
- p.Arg45Trp
- cosmic curated COSV50078
- gnomAD rs1443194987
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.17
- CADD 6.38
- PolyPhen-2 0.76
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available