R45L (p.Arg45Leu) variant of CD79B (P40259)
R45L (p.Arg45Leu) in CD79B (P40259) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R45L (p.Arg45Leu) variant details
- p.Arg45Leu
- TOPMed rs1372057833
- gnomAD rs1372057833
- Missense
- Variant Prioritization Score for Impact Estimate 0.0622
- REVEL 0.05
- CADD 3.05
- PolyPhen-2 0.10
- SIFT 0.30
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available