R3K (p.Arg3Lys) variant of CD79B (P40259)
R3K (p.Arg3Lys) in CD79B (P40259) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R3K (p.Arg3Lys) variant details
- p.Arg3Lys
- rs1387440194
- TOPMed rs1387440194
- gnomAD rs1387440194
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.09
- CADD 6.57
- PolyPhen-2 0.04
- SIFT 0.69
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available