M82V (p.Met82Val) variant of CD79B (P40259)
M82V (p.Met82Val) in CD79B (P40259) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
M82V (p.Met82Val) variant details
- p.Met82Val
- ExAC rs757279256
- TOPMed rs757279256
- gnomAD rs757279256
- Uncertain significance
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.0544
- REVEL 0.05
- CADD 0.23
- PolyPhen-2 0.01
- SIFT 0.28
- ClinVar: Uncertain significance (not specified)
- UniProt: Uncertain significance
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available