G40* (p.Gly40Ter) variant of CD79B (P40259)
G40* (p.Gly40Ter) in CD79B (P40259) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, published literature, and structural context.
G40* (p.Gly40Ter) variant details
- p.Gly40Ter
- gnomAD 17-63931335-C-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.757
- REVEL 0.66
- CADD 52.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available