R55C (p.Arg55Cys) variant of CD7 (T-cell antigen CD7)
R55C (p.Arg55Cys) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R55C (p.Arg55Cys) variant details
- p.Arg55Cys
- rs752636901
- NCI-TCGA Cosmic COSV5394
- cosmic curated COSV53940
- ExAC rs752636901
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.17
- CADD 4.92
- PolyPhen-2 0.50
- SIFT 0.19
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 0.00046)
- Structural context available