R103H (p.Arg103His) variant of CD7 (T-cell antigen CD7)
R103H (p.Arg103His) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
R103H (p.Arg103His) variant details
- p.Arg103His
- rs781698663
- ClinGen CA8856003
- NCI-TCGA Cosmic COSV5393
- cosmic curated COSV53939
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.0666
- REVEL 0.06
- CADD 0.01
- PolyPhen-2 0.01
- SIFT 0.95
- ClinVar: Likely benign (not specified)
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available