R103C (p.Arg103Cys) variant of CD7 (T-cell antigen CD7)
R103C (p.Arg103Cys) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
R103C (p.Arg103Cys) variant details
- p.Arg103Cys
- rs149247674
- cosmic curated COSV53939
- 1000Genomes rs149247674
- ESP rs149247674
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.12
- CADD 22.50
- PolyPhen-2 0.91
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available