L12M (p.Leu12Met) variant of CD7 (T-cell antigen CD7)
L12M (p.Leu12Met) in CD7 (T-cell antigen CD7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
L12M (p.Leu12Met) variant details
- p.Leu12Met
- TOPMed rs1044255902
- gnomAD rs1044255902
- Missense
- Variant Prioritization Score for Impact Estimate 0.0502
- REVEL 0.04
- CADD 0.74
- PolyPhen-2 0.16
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available