L106P (p.Leu106Pro) variant of CD7 (T-cell antigen CD7)
L106P (p.Leu106Pro) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from ClinVar and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
L106P (p.Leu106Pro) variant details
- p.Leu106Pro
- 1000Genomes rs193102571
- ExAC rs193102571
- TOPMed rs193102571
- gnomAD rs193102571
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.0602
- REVEL 0.07
- CADD 0.03
- PolyPhen-2 0.01
- SIFT 0.16
- ClinVar: Likely benign (not specified)
- UniProt: Likely benign
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available