G75R (p.Gly75Arg) variant of CD7 (T-cell antigen CD7)
G75R (p.Gly75Arg) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from ClinVar and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data.
G75R (p.Gly75Arg) variant details
- p.Gly75Arg
- 1000Genomes rs367864176
- ExAC rs367864176
- TOPMed rs367864176
- gnomAD rs367864176
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.059
- REVEL 0.06
- CADD 0.97
- PolyPhen-2 0.14
- SIFT 0.19
- ClinVar: Likely benign (not specified)
- UniProt: Likely benign
- Most common in the 1KG:CDX population (allele frequency 0.011)