G56W (p.Gly56Trp) variant of CD7 (T-cell antigen CD7)
G56W (p.Gly56Trp) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G56W (p.Gly56Trp) variant details
- p.Gly56Trp
- 1000Genomes rs369560649
- ESP rs369560649
- ExAC rs369560649
- TOPMed rs369560649
- Uncertain significance
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.21
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.00
- ClinVar: Uncertain significance (not specified)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the 1KG:ACB population (allele frequency 0.0054)
- Structural context available