G53D (p.Gly53Asp) variant of CD7 (T-cell antigen CD7)
G53D (p.Gly53Asp) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
G53D (p.Gly53Asp) variant details
- p.Gly53Asp
- ExAC rs777449291
- gnomAD rs777449291
- Uncertain significance
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.0983
- REVEL 0.01
- CADD 0.03
- PolyPhen-2 0.00
- SIFT 0.42
- ClinVar: Uncertain significance (not specified)
- UniProt: Uncertain significance
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available