G52W (p.Gly52Trp) variant of CD7 (T-cell antigen CD7)
G52W (p.Gly52Trp) in CD7 (T-cell antigen CD7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G52W (p.Gly52Trp) variant details
- p.Gly52Trp
- rs536476554
- NCI-TCGA Cosmic COSV5393
- cosmic curated COSV53939
- 1000Genomes rs536476554
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.09
- CADD 19.00
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available