V28M (p.Val28Met) variant of CD4 (T-cell surface glycoprotein CD4)
V28M (p.Val28Met) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
V28M (p.Val28Met) variant details
- p.Val28Met
- gnomAD rs1555115041
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.20
- MetaLR 0.37
- MetaSVM -0.61
- CADD 7.91
- PolyPhen-2 0.98
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available