V28A (p.Val28Ala) variant of CD4 (T-cell surface glycoprotein CD4)
V28A (p.Val28Ala) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
V28A (p.Val28Ala) variant details
- p.Val28Ala
- gnomAD rs1555115042
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.16
- MetaLR 0.34
- MetaSVM -0.85
- CADD 23.60
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available